The Biocomputing Unit at the National Centre for Biotechnology (CNB-CSIC) is seeking for a Full-Stack Developer & Scientific Software Engineer to join their unit.
About Scipion: Scipion is an open-source, workflow-oriented software framework used primarily in Cryo-Electron Microscopy (cryoEM). It integrates various scientific software packages into a unified interface, allowing researchers to execute, track, and share complex image-processing pipelines. Its goal is to ensure reproducibility and provide a seamless experience for processing high-resolution biological data.
About ScipionWeb: ScipionWeb is the modern web-based evolution of this framework. It provides a platform to manage scientific projects and workflows: from project creation and protocol execution to high-level visualization and productivity tools.
Stack: React + TypeScript (Frontend) and FastAPI + Python (Backend).
Your Tasks & Evolution
In this role, your responsibilities will evolve as you gain mastery over the framework:
Short to Medium Term:
- 50% Web Development: Full-stack development of the ScipionWeb interface (UI + API + Integration).
- 50% Scipion Core & Domains: Diving into the backend logic, the Scipion core architecture, and specific scientific domains like SPA (Single Particle Analysis) and Tomography.
Medium to Long Term:
- Focus on the Scipion Core and expansion into new scientific domains.
- Maintain and update the ScipionWeb ecosystem to ensure long-term stability.
Requirements
Academic & Language
- Degree: BSc/MSc in Physics, Mathematics, or Software Engineering.
- English: B2 level or equivalent (ability to work in an international environment).
Technical Essentials
- Python: 2+ years of experience with Core Python (Standard Library).
- Linux: Solid basic knowledge (Ubuntu is our preferred distribution).
- Version Control: GitHub (PRs, collaborative workflows).
- DevOps/Distribution: Experience with software distribution (PyPI, Conda) and CI/CD (GitHub Actions).
Stack & Desired Skills
The Tools We Use:
- Frontend: React Router, React Query, MUI, ReactFlow (for diagrams).
- Backend: FastAPI, Pydantic, service-oriented layers.
- Integration: Async workflows (jobs/queues), schema-based forms, and data visualization.
Bonus Points (Desired Skills):
- Knowledge of Image Processing or cryoEM.
- Experience with 3D visualization (three/react-three-fiber or vtk.js).
- Experience with Docker and Celery.
- A strong eye for API design and complex UI (editors, dashboards, large-scale data).
What the Biocomputing Unit Values
We are looking for someone with a scientific mindset—someone who is not only a great coder but is also curious about how pipelines and HPC (High-Performance Computing) environments work. You should enjoy solving complex logic puzzles and building tools that help scientists discover the building blocks of life.
Applying
Are you interested in the Full-Stack Developer and Scientific Software Engineer job position? Send your CV and a letter of interest to blanca@cnb.csic.es.
Original source: https://biocomputingunit.es/2026/02/23/full-stack-developer-scientific-software-engineer-biocomputing-unit/